MAST P 100
Substance : Drostanolone propionate
10 ml
100 mg/ml
Products description: Unique Pharma - MAST P 100
This overview synthesizes information on Drostanolone propionate, the active substance reportedly in Unique Pharma - MAST P 100, from a limited set of key scientific literature and reputable databases. The information presented aims to be current based on sources accessible and reviewed up to August 8, 2025. Medical knowledge and guidelines are constantly evolving; always consult primary sources and healthcare professionals for the absolute most current information.
Drostanolone propionate is a synthetic anabolic-androgenic steroid (AAS), a derivative of dihydrotestosterone (DHT). It is known for its strong androgenic properties and moderate anabolic effects. The propionate ester provides a fast onset of action and a short half-life, requiring more frequent administration [1, 4, 5].
⚕️Established Medical Uses for Drostanolone Propionate
While Drostanolone has a history of medical use, primarily in the treatment of breast cancer, its use has been largely replaced by other, more effective medications [2, 3]:
- Palliative treatment of inoperable breast cancer in postmenopausal women, due to its anti-estrogenic properties [3].
- Today, its use in clinical medicine is very limited, and it is rarely, if ever, prescribed for therapeutic purposes.
🔬Mechanism of Action (Scientifically Described for Drostanolone Propionate)
The primary mechanism of action for drostanolone propionate involves its binding to androgen receptors and its anti-estrogenic properties [1, 4, 5]:
- Ester Cleavage and Drostanolone Release: After intramuscular injection, the propionate ester is rapidly hydrolyzed, releasing free drostanolone into the bloodstream. This fast release provides a strong, immediate effect.
- Androgen Receptor Binding: Drostanolone binds to and activates androgen receptors (ARs) in various tissues. This binding promotes protein synthesis and nitrogen retention, leading to anabolic effects.
- Lack of Aromatization: A key feature of drostanolone is that it is a DHT derivative and does not aromatize into estrogen. This means it does not cause estrogenic side effects like gynecomastia or water retention, which is why it was used to treat breast cancer [3].
⚠️Safety and Adverse Effects (Balanced & Fact-Based for Drostanolone Propionate)
The use of Drostanolone propionate (the active substance in Unique Pharma - MAST P 100) is associated with a range of potential adverse effects, which are generally dose-dependent [1, 2]:
- Androgenic Effects: Due to its high androgenic nature, side effects such as acne, oily skin, accelerated male pattern baldness, and hirsutism (excessive body hair growth) are common. In women, virilization (e.g., deepening of the voice, clitoral enlargement) is a significant risk [2].
- Endocrine Disruption: Exogenous drostanolone strongly suppresses natural testosterone production, which can lead to testicular atrophy and impaired spermatogenesis in men.
- Cardiovascular Risks: It can negatively impact lipid profiles, lowering HDL ("good") cholesterol and increasing LDL ("bad") cholesterol, which increases the risk of cardiovascular disease.
💉Dosage and Administration (General Medical Context for Drostanolone Propionate)
Drostanolone propionate is administered via intramuscular injection. Due to its short half-life, it typically requires frequent injections, often every other day, to maintain stable blood levels [1, 4]:
- Individualized Dosing: The dosage would have been carefully determined by a healthcare professional for its limited medical use.
- Non-Medical Use: Dosages are highly variable and unregulated, based on anecdotal evidence from non-medical communities.
📚References
- DrugBank. Drostanolone Propionate (DB14655). DrugBank Online. Last updated August 8, 2025. https://go.drugbank.com/drugs/DB14655
- PMC. The Use of Anabolic-Androgenic Steroids in the Treatment of HIV/AIDS-Associated Wasting. Accessed August 8, 2025. https://pmc.ncbi.nlm.nih.gov/articles/PMC7145311/
- ScienceDirect. Effect of drostanolone propionate on breast cancer in postmenopausal women. Accessed August 8, 2025. https://www.sciencedirect.com/science/article/abs/pii/0014296477901931
- PubChem. Drostanolone Propionate. National Center for Biotechnology Information. PubChem Compound Database. CID 224004. Accessed August 8, 2025. https://pubchem.ncbi.nlm.nih.gov/compound/224004
- Bioscience.co.uk. Drostanolone Propionate. Accessed August 8, 2025. https://www.bioscience.co.uk/product~1046693
- LGC Standards. Drostanolone Propionate. Accessed August 8, 2025. https://www.lgcstandards.com/TG/en/Drostanolone-Propionate/p/MM3574.00
This information is not medical advice. Consult with a doctor to use this product.